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Treatment of Moderate to Severe Lymphede


Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs

Case 1

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
This is a 61-year-old female who had suffered from breast cancer-related lymphedema of the right upper extremity for 10 years after mastectomy, axillary 19 lymph nodes dissection, and radiotherapy. With the combined use of compression garments and the treatment of complete decongestive therapy, she had developed 2 episodes of cellulitis per year.
At 2- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 27% and 10% above and below the elbow, respectively.
At 2- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 27% and 10% above and below the elbow, respectively.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At 12- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 36% and 15% above and below the elbow, respectively.
The skin paddle in the wrist was de-epithelialized and the left upper medial arm was subjected to liposuction at 14 and 27 months. At 36- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 60% and 10% above and below the elbow, respectively.
The skin paddle in the wrist was de-epithelialized and the left upper medial arm was subjected to liposuction at 14 and 27 months. At 36- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 60% and 10% above and below the elbow, respectively.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At 72- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 100% and 50% above and below the elbow, respectively.
At 75- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 100% and 40% above and below the elbow, respectively.
At 75- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 100% and 40% above and below the elbow, respectively.
Case 2

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At 3- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 38% and 25% above and below the elbow, respectively.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At 6- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 32% and 15% above and below the elbow, respectively.
At 12- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 30% and 15% above and below the elbow, respectively.
At 12- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 30% and 15% above and below the elbow, respectively.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
The skin paddle in the wrist was de-epithelialized and the left upper medial arm was subjected to liposuction at 14 months. At 18- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 90% and 40% above and below the elbow, respectively.
At 22- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 100% and 35% above and below the elbow, respectively.
At 22- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 100% and 35% above and below the elbow, respectively.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At 36- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 100% and 85% above and below the elbow, respectively.
Case 3

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
A 56-year-old patient with grade IV breast cancer-related lymphedema of the left upper extremity for 36 months after modified radical mastectomy, axillary lymph node dissection, and radiation. She developed 5 episodes of cellulitis per year and was refractory to conservative decongestive therapy.
At 12- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 40% and 15% above and below the elbow, respectively.
At 12- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 40% and 15% above and below the elbow, respectively.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
The skin paddle in the wrist was de-epithelialized and the left upper medial arm was subjected to liposuction at 14 months. At 21- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 70% and 30% above and below the elbow, respectively.
At 29- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 100% and 65% above and below the elbow, respectively.
At 29- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 100% and 65% above and below the elbow, respectively.
Case 4

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
A 70-year-old patient with grade III breast cancer-related lymphedema of the left upper extremity for 36 months after modified radical mastectomy, axillary lymph node dissection, and radiation. She developed 1 episodes of cellulitis per year and was refractory to conservative decongestive therapy.
At the 6-months follow-up, vascularized submental lymph node flap transfer to the wrist had significantly improved the patient’s symptoms and extremity tightness. The circumferential reduction rate was 20% above the elbow and 15% below the elbow without the use of a compression garment.
At the 6-months follow-up, vascularized submental lymph node flap transfer to the wrist had significantly improved the patient’s symptoms and extremity tightness. The circumferential reduction rate was 20% above the elbow and 15% below the elbow without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At the 24-months follow-up, the reduction rate was 60% above the elbow and 50% below the elbow without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At the 33-months follow-up, the reduction rate was 50% above the elbow and 25% below the elbow without the use of a compression garment.

Case 5

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
A 59-year-old patient with grade II breast cancer-related lymphedema of the left upper extremity for 12 months after modified radical mastectomy, axillary lymph node dissection, and radiation. She developed 2 episodes of cellulitis per year and was refractory to conservative decongestive therapy.
At the 3-months follow-up, vascularized submental lymph node flap transfer to the wrist had significantly improved the patient’s symptoms and extremity tightness. The circumferential reduction rate was 22% above the elbow and 25% below the elbow without the use of a compression garment.
At the 3-months follow-up, vascularized submental lymph node flap transfer to the wrist had significantly improved the patient’s symptoms and extremity tightness. The circumferential reduction rate was 22% above the elbow and 25% below the elbow without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At the 6-months follow-up, the reduction rate was 35% above the elbow and 25% below the elbow without the use of a compression garment.
At the 12-months follow-up, the reduction rate was 30% above the elbow and 20% below the elbow without the use of a compression garment.
At the 12-months follow-up, the reduction rate was 30% above the elbow and 20% below the elbow without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
The patient received a revision surgery consisting of the de-epithelialization of the skin paddle in the wrist and liposuction for the left upper medial arm 14 months after surgery. At the 24-months follow-up, the reduction rate was 35% above the elbow and 30% below the elbow without the use of a compression garment.
At the 38-months follow-up, the reduction rate was 35% above the elbow and 30% below the elbow. The patient was satisfied with the functional and cosmetic outcomes and did not wear a compression garment.
At the 38-months follow-up, the reduction rate was 35% above the elbow and 30% below the elbow. The patient was satisfied with the functional and cosmetic outcomes and did not wear a compression garment.
Case 6

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
A 51-year-old patient with grade II breast cancer-related lymphedema of the left upper extremity for 6 months after mastectomy, axillary lymph node dissection, and radiation. She developed 1 episodes of cellulitis per year and was refractory to conservative decongestive therapy.
At the 12-months follow-up, the reduction rate was 50% above the elbow and 33% below the elbow without the use of a compression garment.
At the 12-months follow-up, the reduction rate was 50% above the elbow and 33% below the elbow without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At the 12-months follow-up, the reduction rate was 50% above the elbow and 33% below the elbow without the use of a compression garment.
At the 20-months follow-up, the reduction rate was 50% above the elbow and 77% below the elbow without the use of a compression garment.
At the 20-months follow-up, the reduction rate was 50% above the elbow and 77% below the elbow without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At the 20-months follow-up, the reduction rate was 50% above the elbow and 77% below the elbow without the use of a compression garment.
The patient received a revision surgery consisting of the de-epithelialization of the skin paddle in 24 months after surgery. At the 36-months follow-up, the reduction rate was 50% above the elbow and 50% below the elbow without the use of a compression garment.
The patient received a revision surgery consisting of the de-epithelialization of the skin paddle in 24 months after surgery. At the 36-months follow-up, the reduction rate was 50% above the elbow and 50% below the elbow without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
The patient received a revision surgery consisting of the de-epithelialization of the skin paddle in 24 months after surgery. At the 36-months follow-up, the reduction rate was 50% above the elbow and 50% below the elbow without the use of a compression garment.
At the 40-months follow-up, the reduction rate was 70% above the elbow and 75% below the elbow without the use of a compression garment.
At the 40-months follow-up, the reduction rate was 70% above the elbow and 75% below the elbow without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At the 40-months follow-up, the reduction rate was 70% above the elbow and 75% below the elbow without the use of a compression garment.
Case 7

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
A 59-year-old patient with grade II breast cancer-related lymphedema of the left upper extremity for 18 months after modified radical mastectomy, axillary lymph node dissection, and radiation. She developed 2 episodes of cellulitis per year and was received non-vascularized lymph node transfer by other doctor on left elbow, and refractory to conservative decongestive therapy.
At the 3-months follow-up, the reduction rate was 10% above the elbow and 23% below the elbow without the use of a compression garment.
At the 3-months follow-up, the reduction rate was 10% above the elbow and 23% below the elbow without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At the 10-months follow-up, the reduction rate was 20% above the elbow and 30% below the elbow without the use of a compression garment.
The skin paddle in the middle forearm was de-epithelialized and the left upper medial arm was subjected to liposuction at 14 months. At the 20-months follow-up, the reduction rate was 100% above the elbow and 42% below the elbow without the use of a compression garment.
The skin paddle in the middle forearm was de-epithelialized and the left upper medial arm was subjected to liposuction at 14 months. At the 20-months follow-up, the reduction rate was 100% above the elbow and 42% below the elbow without the use of a compression garment.
Case 8

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
This is a 46-year-old female who had suffered from breast cancer-related lymphedema of the right upper extremity for 2 years after mastectomy, axillary lymph node dissection, and radiotherapy. She developed one episode of cellulitis per year with the use of compression garments.
At 3- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 20% and 15% above and below the elbow, respectively.
At 3- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 20% and 15% above and below the elbow, respectively.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At 24- months follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 37% and 20% above and below the elbow, respectively.
At 38- month follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 40% and 25% above and below the elbow, respectively.
At 38- month follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 40% and 25% above and below the elbow, respectively.

Vascularized Lymph Node Flap Transfer (VLNT) - Upper Limbs
At 70- month follow-up, the circumferential reduction rates of the affected limb circumference without the use of compression garments were 75% and 50% above and below the elbow, respectively.

Vascularized Lymph Node Flap Transfer (VLNT) - Lower Limbs

Case 1

Vascularized Lymph Node Flap Transfer (VLNT) - Lower Limbs
A 65-year-old female with grade IV left lower limb lymphedema for 3 years after cervical cancer and radiation.
At the 3 months of follow-up, vascularized submental lymph node flap transfer to the right ankle had significantly improved the symptoms. The circumferential reduction rate was 30% above the knee and 40% below the knee without the use of a compression garment.
At the 3 months of follow-up, vascularized submental lymph node flap transfer to the right ankle had significantly improved the symptoms. The circumferential reduction rate was 30% above the knee and 40% below the knee without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Lower Limbs
At the 9 months of follow-up, vascularized submental lymph node flap transfer to the right ankle had significantly improved the symptoms. The circumferential reduction rate was 10% above the knee and 85% below the knee without the use of a compression garment.
Case 2

Vascularized Lymph Node Flap Transfer (VLNT) - Lower Limbs
A 67-year-old female with grade IV right lower limb lymphedema for 8 years after cervical cancer and radiation. She was refractory to conservative decongestive therapy.
At the 6 months of follow-up, vascularized submental lymph node flap transfer to the right ankle had significantly improved the symptoms. The circumferential reduction rate was 15% above the knee and 5% below the knee without the use of a compression garment.
At the 6 months of follow-up, vascularized submental lymph node flap transfer to the right ankle had significantly improved the symptoms. The circumferential reduction rate was 15% above the knee and 5% below the knee without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Lower Limbs
At the 67 months of follow-up, after flap revision and right lower limb liposuction. The circumferential reduction rate was 62% above the knee and 50% below the knee without the use of a compression garment.
Case 3

Vascularized Lymph Node Flap Transfer (VLNT) - Lower Limbs
This is a 15-year-old patient with left lower limb congenital lymphedema for 2 years.
At the 24 months of follow-up, vascularized submental lymph node flap transfer to the left ankle had significantly improved the symptoms. The circumferential reduction rate was 10% above the knee and 30% below the knee without the use of a compression garment.
At the 24 months of follow-up, vascularized submental lymph node flap transfer to the left ankle had significantly improved the symptoms. The circumferential reduction rate was 10% above the knee and 30% below the knee without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Lower Limbs
At the 36 months of follow-up, after flap revision. The circumferential reduction rate was 10% above the knee and 30% below the knee without the use of a compression garment.
Case 4

Vascularized Lymph Node Flap Transfer (VLNT) - Lower Limbs
This is a 5-year-old patient with right lower limb congenital lymphedema for 2 years.
At the 15 months of follow-up, vascularized submental lymph node flap transfer to the right ankle had significantly improved the symptoms. The circumferential reduction rate was 20% above the knee and 15% below the knee without the use of a compression garment.
At the 15 months of follow-up, vascularized submental lymph node flap transfer to the right ankle had significantly improved the symptoms. The circumferential reduction rate was 20% above the knee and 15% below the knee without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Lower Limbs
At the 13 months of follow-up, after flap revision. The circumferential reduction rate was 25% above the knee and 20% below the knee without the use of a compression garment.

Case 5

Vascularized Lymph Node Flap Transfer (VLNT) - Lower Limbs
This is a 40-year-old patient with left lower limb congenital lymphedema for 15 years.
At the 6 months of follow-up, vascularized submental lymph node flap transfer to the left ankle had significantly improved the symptoms. The circumferential reduction rate was 5% above the knee and 23% below the knee without the use of a compression garment.
At the 6 months of follow-up, vascularized submental lymph node flap transfer to the left ankle had significantly improved the symptoms. The circumferential reduction rate was 5% above the knee and 23% below the knee without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Lower Limbs
At the 36 months of follow-up, after flap revision and left lower limb liposuction. The circumferential reduction rate was 55% above the knee and 56% below the knee without the use of a compression garment.
Case 6

Vascularized Lymph Node Flap Transfer (VLNT) - Lower Limbs
This is a 52-year-old female with grade II left lower limb lymphedema and grade I right lower limb lymphedema for 5 years after cervical cancer and radiation.
At the 1 month of follow-up, vascularized submental lymph node flap transfer to the left ankle had significantly improved the symptoms and extremity tightness. right lower limb was received lymphaticovenous anastomosis without the use of a compression garment.
At the 1 month of follow-up, vascularized submental lymph node flap transfer to the left ankle had significantly improved the symptoms and extremity tightness. right lower limb was received lymphaticovenous anastomosis without the use of a compression garment.

Vascularized Lymph Node Flap Transfer (VLNT) - Lower Limbs
At the 19 months of follow-up, vascularized submental lymph node flap transfer to the left ankle had significantly improved the symptoms and extremity tightness. right lower limb was received lymphaticovenous anastomosis without the use of a compression garment.
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